The relationship between J wave and ventricular tachycardia during Takotsubo cardiomyopathy

Autor: Seong Huan Choi, Oh-Hyun Lee, Gwang-Seok Yoon, Sung Woo Kwon, Sung-Hee Shin, Sang-Don Park, Seong-Ill Woo, Jun Kwan, Dae-Hyeok Kim, Yong-Soo Baek
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: International Journal of Arrhythmia, Vol 21, Iss 1, Pp 1-8 (2020)
Druh dokumentu: article
ISSN: 2466-1171
DOI: 10.1186/s42444-020-00016-6
Popis: Abstract Background and objectives Takotsubo cardiomyopathy (TTC) occasionally causes life-threatening ventricular arrhythmia. J wave on surface electrocardiography (sECG) has also been associated with idiopathic ventricular fibrillation and cardiac events; therefore, we investigated whether the presence of J wave on sECG is a potential risk factor for ventricular arrhythmia in patients with TTC. Subjects and methods We performed a retrospective study in 79 patients who were diagnosed with TTC from 2010 to 2014. Among them, 20 (25.3%) were diagnosed with ventricular tachycardia (VT). The J wave on the sECG was defined as J point elevation manifested through QRS notching or slurring at least 1 mm above the baseline in at least two leads. Results A higher prevalence of ventricular tachycardia was observed in patients with J wave. The corrected QT interval (QTc) was significantly longer in the VT group than in the non-VT group. In a multivariate analysis, the presence of J wave appeared to be the only independent predictors of VT [Hazard Ratio (HR) 3.5, p = 0.019]. Conclusion Our results suggest that the presence of J wave on the sECG is significantly associated with VT, and appear to indicate that the presence of J wave is a strong and independent predictor of VT in patients with TTC.
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