| Autor: |
Man Zhang, Wei Yang, Peng Wang, Yu Deng, Yu-Ting Dong, Fang-Fang Liu, Rui Huang, Peng Zhang, Ya-Qi Duan, Xin-Dong Liu, Dandan Lin, Qian Chu, Bo Zhong |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-020-19973-6 |
| Popis: |
Only a limited proportion of patients with non-small cell lung cancer respond to anti-PD-1/PD-L1 immunotherapy. Here, the authors show that in autochthonous models of KRAS-mutated lung cancer, CCL7 promotes cDC1 infiltration into the lungs, sustaining antitumor immune responses and potentiating anti-PD1 treatment efficacy. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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