| Autor: |
Dadou Said, El Farkhani Mohamed, Hamouti Chahrazade, Elyoussfi Chaimae, Aarab Saida, El Miz Mohamed, Koudad Mohammed, Benchat Noureddine |
| Jazyk: |
English<br />French |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
BIO Web of Conferences, Vol 109, p 01019 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2117-4458 |
| DOI: |
10.1051/bioconf/202410901019 |
| Popis: |
The synthesis of bioactive molecules is of major importance in the pharmaceutical industry. In this context, the study was conducted to determine the antimicrobial and antifungal potential of four chalcone-based imidazo[2,1-b]thiazole derivatives already synthesized by our research group. The synthetized compounds obtained in good yield were evaluated for their antibacterial and antifungal activities against E. coli, Staphylococcus aureus, Pseudomonas aeruginosa and Fusarium, the results obtained are compared with the standard. Molecular docking studies were utilized to forecast the potential of these molecules as antimicrobial agents, the results obtained in vitro antibacterial were well confirmed by this method. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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