Correction of cyclophosphan toxicity by polyphenolic hepatoprotectors
| Autor: | A. S. Saratikov, A. V. Ratjkin, V. N. Frolov, V. S. Chuchalin |
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| Jazyk: | English<br />Russian |
| Rok vydání: | 2004 |
| Předmět: | |
| Zdroj: | Бюллетень сибирской медицины, Vol 3, Iss 1, Pp 52-56 (2004) |
| Druh dokumentu: | article |
| ISSN: | 1682-0363 1819-3684 |
| DOI: | 10.20538/1682-0363-2004-1-52-56 |
| Popis: | Efficiency of lokhein, maksar and karsil hepatoprotectors in the treatment of cyclophosphan damaged liver has been investigated. Hepatoprotectors decrease the overall cytostatic toxicity, reduce the hepatocyte necrosis and the cell infiltration of liver parenchyma, cause the hyperaminotransferase and hyperbilirubin regression, stimulate the bilirubin conjugation and normalize the protein content in blood. Lokhein prevents most efficiently the development of morphologic disturbances in liver and recovers most of biochemical abnormalities at cyclophosphan intoxication. |
| Databáze: | Directory of Open Access Journals |
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