Blood system regulation mechanisms in oxygen insufficiency and participation of neural stem cells in the adaptation to hypoxia

Autor:	Ye. D. Goldberg, A. M. Dygai, G. N. Zyuz’Kov
Jazyk:	English<br />Russian
Rok vydání:	2006
Předmět:	гипоксия энцефалопатия гемопоэз гемопоэзиндуцирующее микроокружение мезенхимальные стволовые клетки нейральные клетки-предшественники hypoxia encephalopathy hemopoiesis hemopoiesis-induced micro-environment mesenchimal stem cells neural cells-precursors Medicine
Zdroj:	Бюллетень сибирской медицины, Vol 5, Iss 2, Pp 43-51 (2006)
Druh dokumentu:	article
ISSN:	1682-0363 1819-3684
DOI:	10.20538/1682-0363-2006-2-43-51
Popis:	Large-scale study of regulation and disadaptation mechanisms of blood system in hypoxia of different genesis is performed. Negative influence of encephalopathy and associated with it adrenergic system activation on hemopoiesis is shown which manifests in disturbed erythropoiesis and production of pathologic forms of erythrocytes. Participation of bone marrow mesenchimal stem cells and increased content of neural cells-precursors in central nervous system in conditions of oxygen deficiency are revealed. Failure of the given adaptation mechanisms of “deep reserve” in severe hypoxia which manifests in the development of encephalopathy and disadaptation of hemopoietic tissue is revealed.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/6aab198f1ae84ba49198294325ae6eeb Zobrazit plný text záznamu View record in DOAJ