Type 2 diabetes in older patients: an analysis of the DPV and DIVE databases

Autor: Gesine van Mark, Sascha R. Tittel, Stefan Sziegoleit, Franz Josef Putz, Mesut Durmaz, Michaela Bortscheller, Ivo Buschmann, Jochen Seufert, Reinhard W. Holl, Peter Bramlage
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Therapeutic Advances in Endocrinology and Metabolism, Vol 11 (2020)
Druh dokumentu: article
ISSN: 2042-0196
20420188
DOI: 10.1177/2042018820958296
Popis: Background: The clinical profile differs between old and young patients with type 2 diabetes mellitus (T2DM). We explored, based on a large real-world database, patient and disease characteristics and actual treatment patterns by age. Methods: The analysis was based on the DIVE and DPV registries of patients with T2DM. Patients were analyzed by age groups 50–59 (middle-young), 60–69 (young-old), 70–79 (middle-old), 80–89 (old), and 90 years or more (oldest-old). Results: A total of 396,719 patients were analyzed, of which 17.7% were 50–59 years, 27.7% 60–69 years, 34.3% 70–79 years, 18.3% 80–89 years and 2.0% at least 90 years. We found that (a) T2DM in old and oldest-old patients was characterized much less by the presence of metabolic risk factors such as hypertension, obesity, dyslipidemia and smoking than in younger patients; (b) the HbA1c was much lower in oldest-old than in middle-young patients (7.2 ± 1.6% versus 8.0 ± 2.2%; p
Databáze: Directory of Open Access Journals