Increased expression of advanced glycation endproducts in the gingival crevicular fluid compromises periodontal status in cigarette-smokers and waterpipe users

Autor: Dena Ali, Fatemah AlAhmari, Toshinari Mikami, Jagan Kumar Baskaradoss
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: BMC Oral Health, Vol 22, Iss 1, Pp 1-7 (2022)
Druh dokumentu: article
ISSN: 1472-6831
DOI: 10.1186/s12903-022-02240-z
Popis: Abstract Background The aim was to assess the association between levels of advanced glycation endproducts (AGEs) in the gingival crevicular fluid (GCF) and periodontal parameters among cigarette-smokers and waterpipe-users. Methods Self-reported cigarette-smokers; waterpipe-users and never-smokers were included. Demographic data was recorded using a questionnaire. Periodontal parameters (plaque index [PI], gingival index [GI], clinical attachment loss [AL], probing depth [PD], and marginal bone loss [MBL]) were assessed in all groups. The GCF samples were collected using standard techniques and assessed for AGEs levels using enzyme-linked immunosorbent assay. Sample-size estimation was done and group-comparisons were done. Correlation between levels of GCF AGEs levels and periodontal parameters was assessed using a logistic regression model. Level of significance was set at P
Databáze: Directory of Open Access Journals