| Autor: |
Tammam Abboud, Günter Hahn, Anita Just, Mihika Paidhungat, Angelina Nazarenus, Dorothee Mielke, Veit Rohde |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Brain Stimulation, Vol 14, Iss 5, Pp 1307-1316 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
1935-861X |
| DOI: |
10.1016/j.brs.2021.08.023 |
| Popis: |
Background: There is a lack of information regarding electrical properties of white matter and brain tumors. Objective: To investigate the feasibility of in-vivo measurement of electrical resistivity during brain surgery and establish a better understanding of the resistivity patterns of brain tumors in correlation to the white matter. Methods: A bipolar probe was used to measure electrical resistivity during surgery in a prospective cohort of patients with brain tumors. For impedance measurement, the probe applied a constant current of 0.7 μA with a frequency of 140 Hz. The measurement was performed in the white matter within and outside peritumoral edema as well as in non-enhancing, enhancing and necrotic tumor areas. Resistivity values expressed in ohmmeter (Ω∗m) were compared between different intracranial tissues and brain tumors. Results: Ninety-two patients (gliomas WHO II:16, WHO III:10, WHO IV:33, metastasis:33) were included. White matter outside peritumoral edema had higher resistivity values (13.3 ± 1.7 Ω∗m) than within peritumoral edema (8.5 ± 1.6 Ω∗m), and both had higher values than brain tumors including non-enhancing (WHO II:6.4 ± 1.3 Ω∗m, WHO III:6.3 ± 0.9 Ω∗m), enhancing (WHO IV:5 ± 1 Ω∗m, metastasis:5.4 ± 1.3 Ω∗m) and necrotic tumor areas (WHO IV:3.9 ± 1.1 Ω∗m, metastasis:4.3 ± 1.3 Ω∗m), p= |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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Full Text from ScienceDirect