Naltrexone, a therapeutic alternative in Darier disease

Autor: Dennise L. Smith-Pellegrin, María R. Rivera-Vega, Jorge R. Cazarín-Barrientos, Aralí Melgarejo-Gómez, Olga M. Messina-Baas, Sergio Cuevas-Covarrubias
Jazyk: English<br />Spanish; Castilian
Rok vydání: 2021
Předmět:
Zdroj: Revista Médica del Hospital General de México, Vol 84, Iss 4 (2021)
Druh dokumentu: article
ISSN: 0185-1063
DOI: 10.24875/HGMX.21000039
Popis: Darier disease is a clinically variable rare disease with autosomal dominant inheritance caused by mutations in ATP2A2 gene. It affects skin, mucous membranes, and nails. The onset of symptoms is during adolescence and persists through adulthood, affecting quality of life. It presents papules and small malodorous keratotic yellow to brown plaques that emerge predominantly in seborrheic areas. In the present study, we describe a patient with Darier disease successfully treated with naltrexone at low doses.
Databáze: Directory of Open Access Journals