Inflammaging: Expansion of Molecular Phenotype and Role in Age-Associated Female Infertility
Autor: | Dmitry Ivanov, Anna Drobintseva, Valeriia Rodichkina, Ekaterina Mironova, Tatyana Zubareva, Yuliya Krylova, Svetlana Morozkina, Maria Greta Pia Marasco, Gianluigi Mazzoccoli, Ruslan Nasyrov, Igor Kvetnoy |
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Jazyk: | angličtina |
Rok vydání: | 2024 |
Předmět: | |
Zdroj: | Biomedicines, Vol 12, Iss 9, p 1987 (2024) |
Druh dokumentu: | article |
ISSN: | 12091987 2227-9059 |
DOI: | 10.3390/biomedicines12091987 |
Popis: | Cellular aging is considered as one of the main factors implicated in female infertility. We evaluated the expression of senescence-associated secretory phenotype (SASP) markers and additional molecular factors in an in vitro model of cellular aging. We induced genotoxic stress (UVB/UVA ray irradiation) in primary human endometrial cells obtained from female subjects of young reproductive age ( |
Databáze: | Directory of Open Access Journals |
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