Inflammaging: Expansion of Molecular Phenotype and Role in Age-Associated Female Infertility

Autor: Dmitry Ivanov, Anna Drobintseva, Valeriia Rodichkina, Ekaterina Mironova, Tatyana Zubareva, Yuliya Krylova, Svetlana Morozkina, Maria Greta Pia Marasco, Gianluigi Mazzoccoli, Ruslan Nasyrov, Igor Kvetnoy
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Biomedicines, Vol 12, Iss 9, p 1987 (2024)
Druh dokumentu: article
ISSN: 12091987
2227-9059
DOI: 10.3390/biomedicines12091987
Popis: Cellular aging is considered as one of the main factors implicated in female infertility. We evaluated the expression of senescence-associated secretory phenotype (SASP) markers and additional molecular factors in an in vitro model of cellular aging. We induced genotoxic stress (UVB/UVA ray irradiation) in primary human endometrial cells obtained from female subjects of young reproductive age (
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