| Autor: |
Sriramya Lapa, Inga Claus, Sarah C. Reitz, Johanna Quick‐Weller, Sonja Sauer, Sigrid Colbow, Christiane Nasari, Rainer Dziewas, Jun‐Suk Kang, Simon Baudrexel, Tobias Warnecke |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Annals of Clinical and Translational Neurology, Vol 7, Iss 7, Pp 1174-1180 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2328-9503 |
| DOI: |
10.1002/acn3.51099 |
| Popis: |
Abstract Objective Deep brain stimulation (DBS) of the ventral intermediate nucleus (VIM) is a mainstay treatment for severe and drug‐refractory essential tremor (ET). Although stimulation‐induced dysarthria has been extensively described, possible impairment of swallowing has not been systematically investigated yet. Methods Twelve patients with ET and bilateral VIM‐DBS with self‐reported dysphagia after VIM‐DBS were included. Swallowing function was assessed clinically and using by flexible endoscopic evaluation of swallowing in the stim‐ON and in the stim‐OFF condition. Presence, severity, and improvement of dysphagia were recorded. Results During stim‐ON, the presence of dysphagia could be objectified in all patients, 42% showing mild, 42% moderate, and 16 % severe dysphagia. During stim‐OFF, all patients experienced a statistically significant improvement of swallowing function. Interpretation VIM‐DBS may have an impact on swallowing physiology in ET‐patients. Further studies to elucidate the prevalence and underlying pathophysiological mechanisms are warranted. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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