Impact of cryoballoon-guided pulmonary vein isolation on non-invasive autonomic tests in patients with paroxysmal atrial fibrillation

Autor: Xavier Galloo, Juan-Pablo Abugattas, Maxime Tijskens, Paul Dendale, Varnavas Varnavas, Michael Wolf, Jeroen De Cocker, Bruno Schwagten, Juan Sieira, Erwin Ströker, Gian-Battista Chierchia, Carlo de Asmundis, Yves De Greef
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Indian Pacing and Electrophysiology Journal, Vol 19, Iss 5, Pp 171-177 (2019)
Druh dokumentu: article
ISSN: 0972-6292
DOI: 10.1016/j.ipej.2019.05.002
Popis: Background: Pulmonary vein isolation (PVI) modulates the intrinsic cardiac autonomic nervous system (ANS). We evaluated the impact of PVI on 5 non-invasive autonomic tests. Methods: Thirty patients (76% male, mean age 60.37 ± 9.02 years) with paroxysmal atrial fibrillation (AF) underwent cryoballoon-guided PVI. Five autonomic tests were performed 24hrs before and after PVI (N = 30) and repeated after 6months (N = 22). Parasympathetic function was measured by heart rate (HR) variability during deep breathing (E/I ratio, I-E difference), Valsalva maneuver (Valsalva-ratio) and head-up tilt test (30/15 ratio). Sympathetic function was measured by systolic BP response to sustained handgrip and 10’ tilting and by diastolic BP response to cold water. Results: 24hrs after PVI, baseline HR increased from 57.93 ± 9.06 bpm to 71.10 ± 12.75 bpm (p
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