| Autor: |
Kendra D. Marr, Natalia A. Ignatenko, Noel A. Warfel, Ken Batai, Anne E. Cress, Grant R. Pollock, Ava C. Wong, Benjamin R. Lee |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Frontiers in Oncology, Vol 12 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2234-943X |
| DOI: |
10.3389/fonc.2022.1083150 |
| Popis: |
The advent of perpetuating living organoids derived from patient tissue is a promising avenue for cancer research but is limited by difficulties with precise characterization. In this brief communication, we demonstrate via time-lapse imaging distinct phenotypes of prostate organoids derived from patient material– without confirmation of cellular identity. We show that organoids derived from histologically normal tissue more readily spread on a physiologic extracellular matrix (ECM) than on pathologic ECM (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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