Genotypic Profile of Streptococcus suis Serotype 2 and Clinical Features of Infection in Humans, Thailand
| Autor: | Kazunori Oishi, Surang Dejsirilert, Parichart Puangpatra, Saowalak Sripakdee, Koranan Chumla, Nitsara Boonkerd, Pitimol Polwichai, Susumu Tanimura, Dan Takeuchi, Tatsuya Nakayama, Shota Nakamura, Yukihiro Akeda, Marcelo Gottschalk, Pathom Sawanpanyalert, Anusak Kerdsin |
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| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: | |
| Zdroj: | Emerging Infectious Diseases, Vol 17, Iss 5, Pp 835-842 (2011) |
| Druh dokumentu: | article |
| ISSN: | 1080-6040 1080-6059 |
| DOI: | 10.3201/eid1705.100754 |
| Popis: | To examine associations between clinical features of Streptococcus suis serotype 2 infections in humans in Thailand and genotypic profiles of isolates, we conducted a retrospective study during 2006–2008. Of 165 patients for whom bacterial cultures of blood, cerebrospinal fluid, or both were positive for S. suis serotype 2, the major multilocus sequence types (STs) found were ST1 (62.4%) and ST104 (25.5%); the latter is unique to Thailand. Clinical features were examined for 158 patients. Infections were sporadic; case-fatality rate for adults was 9.5%, primarily in northern Thailand. Disease incidence peaked during the rainy season. Disease was classified as meningitis (58.9%) or nonmeningitis (41.1%, and included sepsis [35.4%] and others [5.7%]). Although ST1 strains were significantly associated with the meningitis category (p |
| Databáze: | Directory of Open Access Journals |
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