Glanzmann thrombasthenia complicated by frequent myeloproliferative neoplasm‐related thromboembolism: thrombosis occurring regardless of αIIbβIII integrin deficiency

Autor: Roger E. G. Schutgens, Rolf T. Urbanus
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Clinical Case Reports, Vol 9, Iss 9, Pp n/a-n/a (2021)
Druh dokumentu: article
ISSN: 2050-0904
DOI: 10.1002/ccr3.4757
Popis: Abstract A patient with Glanzmann Thrombasthenia developed recurrent venous thrombosis with a JAK2 positive myeloproliferative neoplasm. This indicates that the platelet aIIbβIII integrin has no role in venous thrombosis. We discuss the other potential mechanisms that are involved. In addition, we describe the successful use of dabigatran in this patient.
Databáze: Directory of Open Access Journals
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