Autor: |
Pu-Chun Li, Yi-Fan Zhu, Wen-Ming Cao, Bei Li |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
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Zdroj: |
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-11 (2024) |
Druh dokumentu: |
article |
ISSN: |
2047-783X |
DOI: |
10.1186/s40001-023-01618-1 |
Popis: |
Abstract BRCA2-mutated carriers have a high lifetime risk of breast cancer (BC), an early age of onset, and an increased risk of other cancers (including ovarian, pancreatic, and prostate cancer). Almost 70–80% of BRCA2-mutated BC are estrogen receptor (ER)-positive, which is a particular type of ER-positive BC that differs from sporadic ER-positive BC. This article reviews the clinicopathological features, treatment, and prognosis of ER-positive and BRCA2-mutated BC to provide a reference for clinical decision-making. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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