Gemigliptin: Newer promising gliptin for type 2 diabetes mellitus

Autor: Manish Gutch, Abhay Joshi, Sukriti Kumar, Avinash Agarwal, Rajendra Kumar Pahan, Syed Mohd Razi
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Indian Journal of Endocrinology and Metabolism, Vol 21, Iss 6, Pp 898-902 (2017)
Druh dokumentu: article
ISSN: 2230-8210
DOI: 10.4103/ijem.IJEM_20_17
Popis: The dipeptidyl peptidase-4 (DPP-4) inhibitors have facilitated the management of type 2 diabetes mellitus (T2DM) owing to their superior efficacy and safety with low incidence of adverse effects. Gemigliptin is a new member of this family of drugs, and studies have revealed certain advantages of gemigliptin use compared to its previous congeners. Besides, this drug has also been studied for the treatment of T2DM as monotherapy, in combination with metformin or other oral antidiabetic drugs and in T2DM with moderate-to-severe renal failure. In this review, we explore the published data highlighting the pharmacology, efficacy, and safety of gemigliptin along with its recommendations for use in patients with T2DM.
Databáze: Directory of Open Access Journals