Efficacy and safety of rupatadine in Japanese adult and adolescent patients with chronic spontaneous urticaria: A double-blind, randomized, multicenter, placebo-controlled clinical trial

Autor: Michihiro Hide, Takamasa Suzuki, Ayaka Tanaka, Hiroshi Aoki
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Allergology International, Vol 68, Iss 1, Pp 59-67 (2019)
Druh dokumentu: article
ISSN: 1323-8930
DOI: 10.1016/j.alit.2018.06.002
Popis: Background: Rupatadine, a novel nonsedating second-generation H1-antihistamine with antiplatelet-activating factor activity, has been used in the treatment of allergic rhinitis and urticaria in European countries since 2003. However, its efficacy and safety in Japanese patients with chronic spontaneous urticaria (CSU) are unknown. Methods: We conducted a prospective, multicenter, randomized, placebo-controlled, double-blind study in adolescent and adult CSU outpatients aged 12 to
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