High education accelerates cognitive decline in dementia: A brief report from the population-based NEDICES cohort

Autor: Israel Contador, Félix Bermejo-Pareja, D. Lora Pablos, Alberto Villarejo, Julián Benito-León
Jazyk: angličtina
Předmět:
Zdroj: Dementia & Neuropsychologia, Vol 11, Iss 3, Pp 297-300
Druh dokumentu: article
ISSN: 1980-5764
DOI: 10.1590/1980-57642016dn11-030012
Popis: ABSTRACT High education has been associated with faster cognitive decline after diagnosis of Alzheimer's disease (AD), but it is unclear whether these findings extend to other dementia subtypes. OBJECTIVE: We investigated whether educational attainment influences the cognitive trajectories of older adults with different dementia subtypes. METHODS: All participants were selected from NEDICES, a prospective population-based cohort study of Spanish older adults. A total sample of 53 individuals with dementia completed the MMSE-37 at Times 1 and 2 (mean follow-up=2.8±0.5 years) to assess cognitive decline. RESULTS: At follow-up, MMSE-37 scores had decreased by 3.34±4.98 points in low-educated individuals with dementia versus 7.90±4.88 points in high-educated subjects (effect size (r)=0.32, p=0.02). CONCLUSION: Educational level influenced the cognitive trajectories of patients with dementia assessed by the MMSE-37.
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