APPLICATION EFFECT OF SPUTUM INDUCTION BY ACETYLCYSTEINE AEROSOL INHALATION IN THE DIAGNOSIS OF PULMONARY TUBERCULOSIS IN CHILDREN

Autor: JI Xueqin, CHU Yan, JI Hailing, LI Tongxia
Jazyk: čínština
Rok vydání: 2023
Předmět:
Zdroj: 精准医学杂志, Vol 38, Iss 6, Pp 511-513 (2023)
Druh dokumentu: article
ISSN: 2096-529X
DOI: 10.13362/j.jpmed.202306010
Popis: Objective To investigate the application effect of aerosol inhalation of acetylcysteine in the diagnosis of pulmonary tuberculosis in children. Methods A total of 180 children suspected of pulmonary tuberculosis who were admitted to Qingdao Chest Hospital were enrolled and randomly divided into control group, bronchoscopy group, and acetylcysteine group. For the control group, routine sputum examination (including concentrated smear method, culture method, and GeneXpert test) was performed to identify Mycobacterium tuberculosis; for the bronchoscopy group, routine sputum examination combined with collection of alveolar lavage fluid by bronchoscopy was performed to identify Mycobacterium tuberculosis; for the acetylcysteine group, routine sputum examination combined with collection of sputum after aerosol inhalation of acetylcysteine was performed to identify Mycobacterium tuberculosis. The three groups were compared in terms of the detection rate of Mycobacterium tuberculosis in sputum or alveolar lavage fluid and the incidence rate of adverse reactions. Results There was a significant difference in the detection rate of Mycobacterium tuberculosis between the control group, the bronchoscopy group, and the acetylcysteine group (χ2=9.850,P
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