Phylogenetic analysis and characterization of Korean orf virus from dairy goats: case report

Autor: Jean Young-Hwa, Kim Hye-Ryoung, Lee Kyoung-Ki, Lee Kyung-Hyun, Roh In-Soon, Oem Jae-Ku, Lee O-Soo
Jazyk: angličtina
Rok vydání: 2009
Předmět:
Zdroj: Virology Journal, Vol 6, Iss 1, p 167 (2009)
Druh dokumentu: article
ISSN: 1743-422X
DOI: 10.1186/1743-422X-6-167
Popis: Abstract An outbreak of orf virus infection in dairy goats in Korea was investigated. Suspected samples of the skin and lip of affected goats were sent to the laboratory for more exact diagnosis. Orf virus was detected by electron microscopy and viral DNA was identified by PCR. To reveal the genetic characteristics of the Korean strain (ORF/09/Korea), the sequences of the major envelope protein (B2L) and orf virus interferon resistance (VIR) genes were determined and then compared with published reference sequences. Phylogenetic analysis revealed that the ORF/09/Korea strain was closest to the isolates (Taiping) from Taiwan. This is believed to be the first report on the molecular characterization of orf virus in Korea.
Databáze: Directory of Open Access Journals