| Autor: |
Julia K. Gundersen, Ela Chakkarapani, David A. Menassa, Lars Walløe, Marianne Thoresen |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
BJA Open, Vol 10, Iss , Pp 100283- (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2772-6096 |
| DOI: |
10.1016/j.bjao.2024.100283 |
| Popis: |
Background: Hypothermia is neuroprotective after neonatal hypoxic-ischaemic brain injury. However, systemic cooling to hypothermic temperatures is a stressor and may reduce neuroprotection in awake pigs. We compared two experiments of global hypoxic-ischaemic injury in newborn pigs, in which one group received propofol–remifentanil and the other remained awake during post-insult hypothermia treatment. Methods: In both studies, newborn pigs were anaesthetised using halothane during a 45-min global hypoxic-ischaemic insult induced by reducing Fio2 and graded hypotension until a low-voltage |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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