Relationship between malnutrition and possible sarcopenia in the AWGS 2019 consensus affecting mortality in hemodialysis patients: a prospective cohort study

Autor: Kenichi Kono, Yoshifumi Moriyama, Hiroki Yabe, Ayaka Hara, Takeki Ishida, Tetsuya Yamada, Yusuke Nishida
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: BMC Nephrology, Vol 22, Iss 1, Pp 1-7 (2021)
Druh dokumentu: article
ISSN: 1471-2369
DOI: 10.1186/s12882-021-02566-w
Popis: Abstract Background The first objective of this study was to determine the relationship between muscle strength or physical performance and mortality, and the second objective was to show the relationship of Geriatric Nutritional Risk Index (GNRI) to muscle strength and physical performance decline. Methods We examined handgrip, the 5-times chair stand test, and GNRI in 635 maintenance hemodialysis patients and followed up for 72 months. Predictors for all-cause death were examined using Kaplan-Meier analysis and Cox proportional analysis. The relationship between possible sarcopenia and nutritional disorder (GNRI) was constructed receiver operating characteristic (ROC) curve. We used the Youden index to determine the optimal cutoff points for GNRI. Results The multivariate Cox proportional hazard analysis revealed that the GNRI did not show any significance, although handgrip (HR 3.61, 95% CI 1.70–7.68, p
Databáze: Directory of Open Access Journals
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