Role of Silver Nitrate Spray for Skin Wound Care in Patients with Toxic Epidermal Necrolysis: Our Experience in 4 Patients

Autor: Jose Dario Martinez, Jesus Alberto Cardenas, Manuel Soria, Luis Manuel Saenz, Kattya Estrada, Sergio Maximo Delgado, Marius-Anton Ionescu, Camelia Busila, Alin Laurentiu Tatu
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Life, Vol 13, Iss 12, p 2341 (2023)
Druh dokumentu: article
ISSN: 2075-1729
DOI: 10.3390/life13122341
Popis: Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are examples of severe cutaneous adverse reactions to drugs (SCARs) with several international recommendations for global medical management, ranging from pharmacological systemic therapy to skin wound care. There is no defined best management of the skin wounds in SJS/TEN. The care of wounds is essential to initiate re-epithelialization. Our objective is to improve the cicatrization process, avoiding scarring due to deepening of the wounds, as well as prevent infections, achieve pain control, and avoid loss of serum proteins, fluids, and electrolytes. In this retrospective case series, we highlight the value of systemic therapy and the use of silver nitrate for wound management in four patients with TEN.
Databáze: Directory of Open Access Journals