Infective endocarditis caused by Klebsiella pneumoniae in a patient with non ST elevation myocardial infarction

Autor: Zhilinskiy M.Yu., Mukhina N.V., Komarova I.S., Rachina S.A., Cherkasova N.A., Borisov A.B., Fedina L.V., Nasrulloeva S.M.
Jazyk: ruština
Rok vydání: 2023
Předmět:
Zdroj: Клиническая микробиология и антимикробная химиотерапия, Vol 25, Iss 1, Pp 100-105 (2023)
Druh dokumentu: article
ISSN: 1684-4386
2686-9586
DOI: 10.36488/cmac.2023.1.100-105
Popis: A rare clinical case of native aortic valve infective endocarditis (IE) caused by Klebsiella pneumoniae in a 56-year old man without known risk factors predisposing to the development of IE is presented. Diagnosis of IE in this patient was a challenge due to the lack of recent interventions that could be considered as a source of bacteremia, scarce clinical manifestation and absence of typical complications. Aortic valve vegetation was detected by transesophageal echocardiography. K. pneumoniae isolate was susceptible to all antibiotics tested. Antibacterial therapy (cefepime 6 g/day IV for 2 weeks in the hospital followed by ceftriaxone 4 g/day IM and cefixime 400 mg/day PO, a total of 4 weeks as an outpatient) resulted in a complete resolution of IE signs and symptoms, laboratory abnormalities as well as vegetation size decrease. Surgical treatment was not required in this patient.
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