| Autor: |
Jaana Korpela, Juho Joutsa, Juha O. Rinne, Jörgen Bergman, Valtteri Kaasinen |
| Jazyk: |
angličtina |
| Rok vydání: |
2015 |
| Předmět: |
|
| Zdroj: |
Tremor and Other Hyperkinetic Movements, Vol 5 (2015) |
| Druh dokumentu: |
article |
| ISSN: |
2160-8288 |
| DOI: |
10.7916/D8PV6JMT |
| Popis: |
Background: The pathophysiology of the movement disorder progressive ataxia with palatal tremor (PAPT) is unclear.Case report: A 77-year-old male presented with dysarthria, ataxia, and 1–2 Hz palatal tremor. A diagnosis of probable sporadic PAPT was established. Brain magnetic resonance imaging was normal at the presymptomatic phase but later showed olivary hypertrophy. Brain [18F]-fludeoxyglucose (FDG) positron emission tomography (PET) showed bilateral hypermetabolism in the olivary nuclei. Discussion: This second reported patient with PAPT and FDG-PET shows that olivary hypertrophy is paralleled with hypermetabolism. The olivary nuclei pathology also appears to be temporally associated with symptom onset. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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