Coupling Pyrazine to Dithiocarbonates for Molybdopterin Model Ligands—Indispensable Tin

Autor:	Siva Sankar Murthy Bandaru, Claudia Schindler, Felix Wenzek, Carola Schulzke
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	Stille reaction stannylation copper(I)-thiophene-2-carboxylate 4-(pyrazin-2-yl)-1 3-dithiol-2-one ligand systems acetalization Inorganic chemistry QD146-197
Zdroj:	Inorganics, Vol 11, Iss 5, p 188 (2023)
Druh dokumentu:	article
ISSN:	2304-6740
DOI:	10.3390/inorganics11050188
Popis:	Several synthetic cross-coupling procedures were (re-)evaluated for the tethering of pyrazine to dithiocarbonates. The resultant species constitute pro-ligands and can be converted by removal of the C=O moiety into ene-dithiolate ligand systems that model molybdopterin. The coupling of 2-iodopyrazine with the stannylated dithiocarbonate units mediated by copper(I)-thiophene-2-carboxylate in stoichiometric equivalents proved to be the most efficient and the only reliable route to the targeted compounds. Single-crystal X-ray structural analysis confirmed the final structures of two pursued pyrazine-derived dithiocarbonates and those of two intermediates.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/697e20c5b3294a7ebdc434e5468b09a4 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
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