Planar chiral 2-(trifluoromethyl)quinoline-fused ferrocenes via palladium(0)-catalyzed C-H functionalization of trifluoroacetimidoyl chlorides

Autor: An-An Zhang, Chao Chen, Yushen Gao, Mingyang Mo, Ren-Zeng Shen, Yu-Heng Zhang, Naoki Ishida, Masahiro Murakami, Lantao Liu
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Green Synthesis and Catalysis, Vol 2, Iss 3, Pp 311-314 (2021)
Druh dokumentu: article
ISSN: 2666-5549
DOI: 10.1016/j.gresc.2021.05.004
Popis: Catalytic enantioselective synthesis of planar chiral 2-(trifluoromethyl)quinoline-fused ferrocenes has been achieved through Pd(0)-catalyzed C-H functionalization with trifluoroacetimidoyl chlorides as electrophilics. With commercially available ligand and palladium precursor, the reaction proceeds smoothly generating 2-perfluoroalkylated quinoline-fused ferrocenes in high yields and enantioselectivities.
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