Pancreatic cancer prognosis is predicted by an ATAC-array technology for assessing chromatin accessibility

Autor: S. Dhara, S. Chhangawala, H. Chintalapudi, G. Askan, V. Aveson, A. L. Massa, L. Zhang, D. Torres, A. P. Makohon-Moore, N. Lecomte, J. P. Melchor, J. Bermeo, A. Cardenas, S. Sinha, D. Glassman, R. Nicolle, R. Moffitt, K. H. Yu, S. Leppanen, S. Laderman, B. Curry, J. Gui, V. P. Balachandran, C. Iacobuzio-Donahue, R. Chandwani, C. S. Leslie, S. D. Leach
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-021-23237-2
Popis: ATAC-seq allows for the investigation of chromatin accessibility, a feature which can have important implications for gene regulation. Here the authors present ATAC-array to assess accessibility in human tumours and based on this predict disease prognosis.
Databáze: Directory of Open Access Journals