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Heba Mohamed Abd Elgalil, Asmaa Abdelghany Elsheikh, Doaa Sadek Ahmed, Amal M Ahmed, Soso Shawky Mohamed Community and Occupational Medicine Department, Faculty of Medicine, Al-Azhar University, Cairo, EgyptCorrespondence: Heba Mohamed Abd Elgalil, Community and Occupational Medicine Department. Faculty of Medicine, Al -Azhar University, Cairo, Egypt, Tel +20- 01153411236, Email Hebamohamed.medg@azhar.edu.egBackground: There are still many concerns related to various types of COVID-19 vaccines, which may result in individuals’ hesitancy presenting a problem for public health authorities to achieve coverage for population immunity. As trustworthy health-care workers, medical and nursing students’ perception towards COVID-19 vaccines may greatly influence the future population’s uptake of vaccines; however, studies related to the vaccine acceptance rates among them are limited.Objective: To identify the perception of medical and nursing students toward COVID-19 vaccines and the factors acting either as motivators or barriers to be vaccinated.Methods: A cross-sectional comparative study was conducted on 500 undergraduate students aged ≥ 18 years from medical and nursing faculties. Data were collected via a semi-structured self-administered questionnaire that consisted of questions on general characteristics of the participants and source of information about the vaccine. Also, it includes items assessing the perception and acceptance of COVID-19 vaccines. Descriptive statistics, chi-squared, t-test and multiple logistic regressions were performed using SPSS version 22.Results: Positive perception was detected among more than half of overall students. Although medical students had significant higher positive perception toward COVID-19 vaccines than nursing students (54.9% vs. 41.1%, p < 0.05), they were more hesitant to get vaccinated than nursing students (25.7% vs. 19.6%, p > 0.05). While, medical students had a higher intention to encourage family members or friends to get vaccinated than did nursing students (47.7% vs .43.8%, respectively) (p > 0:05). Furthermore, participants were more likely to accept vaccination if they reported higher levels of positive perception especially for vaccine safety and increasing recovery rate.Conclusion: Academic medical and nursing leaders should consider female students’ vaccine concerns, and future efforts are needed to reduce their hesitancy and raise awareness about vaccinations that may eventually improve perception and acceptance of COVID-19 vaccines.Keywords: COVID-19, medical students, vaccine acceptance, nursing students, Egypt |