| Autor: |
XU Qian, DUAN Hua, GAN Lu, LIU Qiwei |
| Jazyk: |
čínština |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Jichu yixue yu linchuang, Vol 43, Iss 2, Pp 301-305 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
1001-6325 |
| DOI: |
10.16352/j.issn.1001-6325.2023.02.301 |
| Popis: |
Epithelial-mesenchymal transition (EMT) is a process by which epithelial cells undergo morphological changes to gain a mesenchymal cell phenotype and migratory properties. As a class of negative regulators of RhoGTPases, RhoGTPase activating proteins(RhoGAP) can bridge between cell surface receptors and cellular actin cytoskeleton during EMT procedure, which may influence cancer cell transition and outcome of fibrotic diseases and may help search for anti-tumor and anti-fibrotic managements. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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