Dynamic changes in intestinal microbiota in young forest musk deer during weaning

Autor: Yimeng Li, Minghui Shi, Tianxiang Zhang, Xin Hu, Baofeng Zhang, Shanghua Xu, Jianhong Ding, Defu Hu, Shuqiang Liu
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: PeerJ, Vol 8, p e8923 (2020)
Druh dokumentu: article
ISSN: 2167-8359
DOI: 10.7717/peerj.8923
Popis: Weaning is an important event for all mammals, including young forest musk deer. However, weaning stress may cause intestinal microbiota-related disorders. Therefore, high-throughput 16S rRNA gene sequencing was applied to study the dynamic changes in intestinal microbiota during pre-weaning (10 days before weaning) and post-weaning (10 days after weaning) in 15 young forest musk deer. We saw that intestinal microbiota diversity in the post-weaning period was significantly higher than that in the pre-weaning period. The most dominant bacterial phyla were similar in the two groups (Firmicutes, Bacteroidetes and Verrucomicrobia). Meanwhile, we applied Linear discriminant analysis effect size (LefSe) to identify the most differentially microbial taxa in the pre-weaning and post-weaning groups. In the post-weaning forest musk deer, the relative abundance of Actinobacteria, Spirochaetes, Ruminococcaceae_UCG-005, Treponema and Prevotella was higher than in the pre-weaning group. However, higher relative abundance of the phyla Bacteroidetes was found in the pre-weaning group compared with that in the post-weaning group. In summary, this research provides a theoretical foundation for the dynamics of young forest musk deer intestinal microbiota during the weaning transition, which may benefit in understanding the growth and health of forest musk deer.
Databáze: Directory of Open Access Journals