High Prevalence of Metabolic Syndrome in Patients with Discoid Lupus Erythematosus: A Cross-Sectional, Case-Control Study

Autor: Sevgi Akarsu, Ozlem Ozbagcivan, Fatma Semiz, Sebnem Aktan
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Journal of Immunology Research, Vol 2017 (2017)
Druh dokumentu: article
ISSN: 2314-8861
2314-7156
DOI: 10.1155/2017/3972706
Popis: Although it is known that systemic form of lupus erythematosus (LE) and metabolic syndrome (MetS) are frequently observed together, there are no published reports on MetS in patients with skin-restricted LE. We aimed to compare the frequencies of MetS and its components in discoid LE (DLE) with the non-DLE control group. Additionally, we intended to determine the differences of sociodemographic and clinical data of the DLE patients with MetS compared to the patients without MetS. This was a cross-sectional, case-control study, including 60 patients with DLE and 82 age- and gender-matched control subjects. In DLE group, the presence of MetS was observed as more frequent (48.3% versus 24.4%, p=0.003), and hypertriglyceridemia (43.3% versus 22.0%, p=0.006) and reduced HDL-cholesterol (61.7% versus 23.2%, p
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