Autor: |
Vincenzo Russo, MD, PhD, MMsc, Anna Rago, MD, Bruno Pannone, (MD), Maria Carolina Mayer, MD, Anna Spasiano, MD, Raffaele Calabro, MD, PhD, Maria Giovanna Russo, MD, Nigro Gerardo, MD, PhD |
Jazyk: |
angličtina |
Rok vydání: |
2014 |
Předmět: |
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Zdroj: |
Indian Pacing and Electrophysiology Journal, Vol 14, Iss 3, Pp 121-132 (2014) |
Druh dokumentu: |
article |
ISSN: |
0972-6292 |
DOI: |
10.1016/S0972-6292(16)30753-7 |
Popis: |
Background: Paroxysmal atrial tachyarrhythmias frequently occur in beta-thalassemia major (β-TM) patients.The aim of our study was to investigate the role of maximum P-wave duration (P max) and dispersion (PD), calculated trough a new manually performed measurement with the use of computer software from all 12-ECG-leads, as predictors of atrial-fibrillation (AF)in β-TM patients with conserved systolic or diastolic cardiac function during a twelve-months follow-up. Materials and Methods: 50 β-TM-patients (age38.4±10.1; 38M) and 50-healthy subjects used as controls, matched for age and gender, were studied for the occurrence of atrial arrhythmias during a 1-year follow-up, through ECG-Holter-monitoring performed every three months. The β-TM-patients were divided into two groups according to number and complexity of premature-supraventricular-complexes at the Holter-Monitoring (Group1: 30/h or couplets, or run of supraventricular tachycardia and AF, n:15). Results: Compared to the healthy control-group, β-TM patients presented increased P-max (107.5± 21.2 vs 92.1±11ms, P=0.03) and PD-values (41.2±13 vs 25.1±5 ms, P=0.03). In the β-TM population, the Group2 showed a statistically significant increase in PD (42.8±8.6 vs 33.2±6.5ms, P |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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