Autor: |
Nayelli Marsch-Martínez, J. Irepan Reyes-Olalde, Antonio Chalfun-Junior, Marian Bemer, Yolanda Durán-Medina, Juan Carlos Ochoa-Sánchez, Herenia Guerrero-Largo, Humberto Herrera-Ubaldo, Jurriaan Mes, Alejandra Chacón, Rocio Escobar-Guzmán, Andy Pereira, Luis Herrera-Estrella, Gerco C. Angenent, Luis Delaye, Stefan de Folter |
Jazyk: |
angličtina |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
iScience, Vol 25, Iss 12, Pp 105627- (2022) |
Druh dokumentu: |
article |
ISSN: |
2589-0042 |
DOI: |
10.1016/j.isci.2022.105627 |
Popis: |
Summary: Evolution has long been considered to be a conservative process in which new genes arise from pre-existing genes through gene duplication, domain shuffling, horizontal transfer, overprinting, retrotransposition, etc. However, this view is changing as new genes originating from non-genic sequences are discovered in different organisms. Still, rather limited functional information is available. Here, we have identified TWISTED1 (TWT1), a possible de novo-originated protein-coding gene that modifies microtubule arrangement and causes helicoidal growth in Arabidopsis thaliana when its expression is increased. Interestingly, even though TWT1 is a likely recent gene, the lack of TWT1 function affects A. thaliana development. TWT1 seems to have originated from a non-genic sequence. If so, it would be one of the few examples to date of how during evolution de novo genes are integrated into developmental cellular and organismal processes. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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