MODELLING AND SIMULATION OF A NEUROPHYSIOLOGICAL EXPERIMENT BY SPATIO-TEMPORAL POINT PROCESSES

Autor: Viktor Beneš, Blažena Frcalová
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Image Analysis and Stereology, Vol 27, Iss 1, Pp 47-52 (2011)
Druh dokumentu: article
ISSN: 1580-3139
1854-5165
DOI: 10.5566/ias.v27.p47-52
Popis: We present a stochastic model of an experimentmonitoring the spiking activity of a place cell of hippocampus of an experimental animal moving in an arena. Doubly stochastic spatio-temporal point process is used to model and quantify overdispersion. Stochastic intensity is modelled by a Lévy based random field while the animal path is simplified to a discrete random walk. In a simulation study first a method suggested previously is used. Then it is shown that a solution of the filtering problem yields the desired inference to the random intensity. Two approaches are suggested and the new one based on finite point process density is applied. Using Markov chain Monte Carlo we obtain numerical results from the simulated model. The methodology is discussed.
Databáze: Directory of Open Access Journals