| Autor: |
I. A. Kryvoruchko, S. M. Teslenko, N. M. Goncharova, V. F. Gontar, N. A. Alexandrov, P. V. Svirepo |
| Jazyk: |
English<br />Spanish; Castilian<br />Polish<br />Russian<br />Ukrainian |
| Rok vydání: |
2017 |
| Předmět: |
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| Zdroj: |
Journal of Education, Health and Sport, Vol 7, Iss 2, Pp 523-536 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
2391-8306 |
| DOI: |
10.5281/zenodo.399311 |
| Popis: |
Background. Differential diagnostics of chronic pancreatitis and the pancreas cancer with prevalent affection of head is on of the most difficult and important problems of surgical pancreatology. Methods. Analyzed the results of surgical treatment of 132 patients, including 68 - for cancer of the pancreatic head (in 46 - with jaundice) and 64 - chronic pancreatitis (CP) with a primary lesion of the pancreatic head (16 - with jaundice). The distribution of patients into groups was carried out with a maximum value of classification functions calculated by special formulas. Next studied indicators of endothelial dysfunction for differential diagnosis. Results. It was defined the threshold of VEGF = 346 pg/ml, which shared the group of chronic pancreatitis or cancer of the pancreatic head, which was determined based on the Pareto criterion. This model sensitivity was 72.1% and specificity of 75% for the overall accuracy of 72.7%. Even more precision indicator was on the threshold of VEGF = 248 pg/ml, which compared groups of patients with cancer and software of the control group (125.9 pg/ml) and the sensitivity was 86.8%, specificity 82.4%, and overall accuracy of 82.3%. At about the same accuracy had this test and the comparison group of patients with chronic pancreatitis and control: sensitivity 84.4% and specificity of 76.5% overall accuracy of 81.5% in the threshold VEGF of 155 pg/ml (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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