| Autor: |
Namburi Suresh, Gutta Lakshmi Prasanna, A. Ratnakar, Mandava Venkata Basaveswara Rao, Manojit Pal |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Arabian Journal of Chemistry, Vol 12, Iss 8, Pp 5370-5379 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
1878-5352 |
| DOI: |
10.1016/j.arabjc.2017.01.007 |
| Popis: |
An ultrasound assisted method has been developed for the Pd-mediated synthesis of indole derivatives in good to acceptable yields. The methodology involved Pd/C-catalyzed coupling–cyclization of 2-iodosulfanilide with alkynes under ultrasound irradiation in the presence of LiCl and NaHCO3 in DMF. A variety of internal/terminal alkynes was employed in this CC followed by CN bond forming reaction to afford the corresponding indoles. Being faster and milder method the present ultrasound-based approach appeared to be a useful and cheaper alternative to the existing methods. Keywords: Ultrasound, Pd/C, Indole, Alkyne |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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