| Autor: |
Isoppo de Souza Caroline, Rosa Daniela Dornelles, Ettrich Betina, Cibeira Gabriela Hermann, Giacomazzi Juliana, Tusset Paloma, Ashton-Prolla Patrícia, Medeiros Lidia Rosi, Caleffi Maira, Neto Eurico Camargo, Moriguchi Emilio Hideyuki, Graudenz Marcia Silveira |
| Jazyk: |
angličtina |
| Rok vydání: |
2012 |
| Předmět: |
|
| Zdroj: |
Nutrition & Metabolism, Vol 9, Iss 1, p 97 (2012) |
| Druh dokumentu: |
article |
| ISSN: |
1743-7075 |
| DOI: |
10.1186/1743-7075-9-97 |
| Popis: |
Abstract Background The soluble cell adhesion molecules and adipokines are elevated in patients with obesity, hypertension, type 2 diabetes mellitus, breast cancer and atherosclerosis. Objective To investigate the relationship between anthropometric profile, dietary intake, lipid profile and fasting glycemia with serum levels of adipokines (adiponectin and PAI-1) and adhesion molecules (ICAM-1 and VCAM-1) in women without breast cancer undergoing routine mammographic screening. Design Transversal study. Subjects One hundred and forty-five women over 40-years old participated in this study. Results In 39.3% of cases the BMI was above 30 kg/m2; 46.9% had hypertension, 14.5% had type 2 Diabetes Mellitus, 31.7% had dyslipidemia and 88.3% presented a waist-to-hip ratio ≥ 0.8. A linear correlation was found between serum levels of PAI-1 and triglycerides, between serum levels of PAI-1 and WHR and between serum levels of VCAM-1 and BMI. Conclusion We found a high prevalence of obesity and metabolic syndrome. PAI-1 and VCAM-1 levels were correlated with clinical indicators of obesity and overweight. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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