Appendicular Skeletal Muscle Mass and Insulin Resistance in an Elderly Korean Population: The Korean Social Life, Health and Aging Project-Health Examination Cohort
| Autor: | Seung Won Lee, Yoosik Youm, Won Joon Lee, Wungrak Choi, Sang Hui Chu, Yeong-Ran Park, Hyeon Chang Kim |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | Diabetes & Metabolism Journal, Vol 39, Iss 1, Pp 37-45 (2015) |
| Druh dokumentu: | article |
| ISSN: | 2233-6079 2233-6087 |
| DOI: | 10.4093/dmj.2015.39.1.37 |
| Popis: | BackgroundIncreasing evidence supports an association between age-related loss of muscle mass and insulin resistance. However, the association has not been fully investigated in the general population. Thus, we investigated the association between appendicular skeletal muscle mass (ASM) and insulin resistance in an elderly Korean population.MethodsThis cross-sectional study included 158 men (mean age, 71.8) and 241 women (mean age, 70.6) from the Korean Social Life, Health and Aging Project, which started in 2011. In this study, ASM was measured by bioelectrical impedance analysis and was analyzed in three forms: ASM (kg), ASM/height2 (kg/m2), and ASM/weight (%). The homeostasis model assessment of insulin resistance (HOMA-IR) was used as a measure of insulin resistance. The relationships between the ASM values and the HOMA-IR were investigated by multiple linear regression models.ResultsThe HOMA-IR was positively associated with ASM (β=0.43, P |
| Databáze: | Directory of Open Access Journals |
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