| Autor: |
Jun'ichi Kobayashi, Kunimi Kikuchi, Naohito Aoki, Shinya Mitsuhashi, Tadashi Okada, Hiroshi Shima, Takaaki Kubota, Yusuke Wakuda |
| Jazyk: |
angličtina |
| Rok vydání: |
2006 |
| Předmět: |
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| Zdroj: |
Marine Drugs, Vol 4, Iss 1, Pp 9-14 (2006) |
| Druh dokumentu: |
article |
| ISSN: |
1660-3397 |
| DOI: |
10.3390/md401009 |
| Popis: |
Abstract: Manzamenones A~C (1~3) and E~F (5~6), unique oxylipin metabolites isolated from a marine sponge Plakortis sp., have been found to exhibit inhibitory activity against Tcell protein tyrosine phosphatase (TCPTP). The inhibitory activity of 2 and 5 against TCPTP was 4 times more potent than that against protein tyrosine phosphatase-1B (PTP1B). |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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