Recent Advances in Adjuvant Therapy for Non–Small-Cell Lung Cancer

Autor:	Mi-Hyun Kim, Soo Han Kim, Min Ki Lee, Jung Seop Eom
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	carcinoma non-small-cell lung chemotherapy adjuvant molecular targeted therapy immunotherapy Diseases of the respiratory system RC705-779
Zdroj:	Tuberculosis and Respiratory Diseases, Vol 87, Iss 1, Pp 31-39 (2024)
Druh dokumentu:	article
ISSN:	1738-3536 2005-6184
DOI:	10.4046/trd.2023.0085
Popis:	After the successful development of targeted therapy and immunotherapy for the treatment of advanced-stage non-small cell lung cancer (NSCLC), these innovative treatment options are rapidly being applied in the adjuvant setting for early-stage NSCLC. Some adjuvants that have recently been approved include osimertinib for epidermal growth factor receptor-mutated tumors and atezolizumab and pembrolizumab for selected patients with resectable NSCLC. Numerous studies on various targeted therapies and immunotherapy with or without chemotherapy are currently ongoing in the adjuvant setting. However, several questions regarding optimal strategies for adjuvant treatment remain unanswered. The present review summarizes the available literature, focusing on recent advances and ongoing trials with targeted therapy and immunotherapy in the adjuvant treatment of early-stage NSCLC.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/69257ae197d94cda913a0898432e0e3e Zobrazit plný text záznamu View record in DOAJ