Phenolic compounds and anticancer activity of commercial sugarcane cultivated in Brazil
| Autor: | VANESSA G. ALVES, ALAN G. SOUZA, LUCAS U.R. CHIAVELLI, ANA L.T.G. RUIZ, JOÃO E. CARVALHO, ARMANDO M. POMINI, CLEUZA C. SILVA |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | Anais da Academia Brasileira de Ciências, Iss 0 (2016) |
| Druh dokumentu: | article |
| ISSN: | 1678-2690 0001-3765 |
| DOI: | 10.1590/0001-3765201620150349 |
| Popis: | ABSTRACT The cultivation of sugarcane hybrids (X Saccharum officinarum L.) is an important revenue source for the Brazilian economy. Herein it is reported the evaluation of the cytotoxic activity of mid-polarity sugarcane extracts against human cancer cell lines, as well as the isolation of steroids sitosterol, stigmasterol and campesterol, phenolic acids p-hydroxybenzoic, p-hydroxycinnamic, vanillic and ferulic acid, terpenoids α-tocopherol and β-carotene and a novel substance in sugarcane, the flavonoid aglycone tricin (5,7,4-trihydroxy-3,5-dimethoxyflavone). The presence of large amounts of phenolic acids and the flavonoid tricin may explain the cytostatic activity observed for the mid-polarity crude extract and filtrates. |
| Databáze: | Directory of Open Access Journals |
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