Seroprevalence of Helicobacter pylori infection and risk factors among patients presenting with symptoms of peptic ulcer in Akure metropolis
| Autor: | Patience Abbah, TINUOLA ADEBOLU, Babayemi Oladejo |
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| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Microbes and Infectious Diseases, Vol 4, Iss 4, Pp 1296-1306 (2023) |
| Druh dokumentu: | article |
| ISSN: | 2682-4132 2682-4140 |
| DOI: | 10.21608/mid.2023.192688.1465 |
| Popis: | Background: Helicobacter pylori (H. pylori) is a causative agent of peptic ulcer which presently affects more than half of the world's population. This study determined H. pylori prevalence and risk variables among peptic ulcer patients in Akure, Ondo State, Nigeria. Methods: Two-hundred (200) study participants consented at local hospitals. A pre-tested, structured questionnaire collected socio-demographic and risk factor information from participants. Participants' blood samples were tested with a fast chromatographic immunoassay kit for H. pylori antibodies. Results: 73.5 %of the 200 tested subjects had H. pylori. Prevalence was greater among women (74.8%) than men (71.6%). The most heavily impacted age group for H. pylori infection is 21–30 years with 78.4% prevalence, while the least affected is 51–60 years with 66.7% prevalence. Married respondents (77.2%) had a greater prevalence of H. pylori than singles (71.1%). The difference in prevalence rate based on individuals' education and occupation was not statistically significant (p=0.407 and 0.999, respectively). Helicobacter pylori infection was significantly associated with NSAID use (X2= 8.917, p= |
| Databáze: | Directory of Open Access Journals |
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