Mechanical Thrombectomy for In-Hospital Onset Stroke: A Comparative Systematic Review and Meta-Analysis

Autor: Melika Amoukhteh, Amir Hassankhani, Sherief Ghozy, Parya Valizadeh, Payam Jannatdoust, Cem Bilgin, Ramanathan Kadirvel, David F. Kallmes
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Stroke, Vol 26, Iss 1, Pp 41-53 (2024)
Druh dokumentu: article
ISSN: 2287-6391
2287-6405
DOI: 10.5853/jos.2023.01613
Popis: Background and Purpose In-hospital onset stroke (IHOS) accounts for a significant proportion of large vessel occlusion acute ischemic strokes, leading to worse outcomes due to delays in evaluation and treatment. Limited data is available on the effectiveness of mechanical thrombectomy in IHOS patients. This study aims to assess the safety and efficacy of mechanical thrombectomy for patients with IHOS and compare the outcomes with those of community-onset strokes (COS). Methods We conducted a systematic review and meta-analysis following established guidelines, by searching PubMed, Scopus, Web of Science, and Embase databases up to April 11, 2023. Eligible studies reporting outcomes of interest were included, and relevant data was extracted and analyzed using Stata software version 17.0. Results In a meta-analysis of nine studies, comprising 540 cases of IHOS and 5,744 cases of COS, IHOS cases had a significantly lower rate of good functional outcomes on follow-up (35.46% vs. 40.74%, P
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