Analysis of the Risk Factors for Mortality in Adult COVID-19 Patients in Wuhan: A Multicenter Study

Autor: Man Li, Biao Cheng, Wen Zeng, Sichao Chen, Mengqi Tu, Meng Wu, Wei Tong, Shipei Wang, Yihui Huang, Wei Long, Wei Zhou, Danyang Chen, Lin Zhou, Min Wang, Haibo Xu, Aiping Deng, Zeming Liu, Liang Guo
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Frontiers in Medicine, Vol 7 (2020)
Druh dokumentu: article
ISSN: 2296-858X
DOI: 10.3389/fmed.2020.00545
Popis: Objectives: An outbreak of coronavirus disease (COVID-19) in 2019 in Wuhan, China, has spread quickly worldwide. However, the risk factors associated with COVID-19-related mortality remain controversial.Methods: A total of 245 adult patients with laboratory-confirmed COVID-19 from two centers were analyzed. Chi-square, Fisher's exact, and the Mann-Whitney U-tests were used to compare the clinical characteristics between the survivors and non-survivors. To explore the risk factors associated with in-hospital death, univariable and multivariable cox regression analyses were used.Results: Of the 245 patients included in this study, 23 (9.4%) died in the hospital. The multivariate regression analysis showed increased odds of in-hospital deaths associated with age, D-dimer levels >1,000 ng/L, platelet count
Databáze: Directory of Open Access Journals