Associations of serum long-chain fatty acids with multiple organ involvement in patients with sarcoidosis

Autor: Takahito Suzuki, Masato Karayama, Yusuke Inoue, Hironao Hozumi, Yuzo Suzuki, Kazuki Furuhashi, Tomoyuki Fujisawa, Noriyuki Enomoto, Yutaro Nakamura, Naoki Inui, Takafumi Suda
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: BMC Pulmonary Medicine, Vol 22, Iss 1, Pp 1-9 (2022)
Druh dokumentu: article
ISSN: 1471-2466
DOI: 10.1186/s12890-022-02084-x
Popis: Abstract Background Fatty acids have diverse immunomodulatory functions and the potential to be associated with inflammatory responses in sarcoidosis. Methods The serum levels of multiple long-chain fatty acids (LCFAs) were compared between 63 patients with sarcoidosis and 38 healthy controls. The associations of LCFAs with clinical outcomes of sarcoidosis were also evaluated. Results The patients with sarcoidosis had significantly lower levels of n-3 poly-unsaturated fatty acids (PUFAs) (p
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