Long-term functional outcome and quality of life 2.5 years after thrombolysis in acute ischemic stroke

Autor: Marie Schäbitz, Leona Möller, Anja Friedrich, Nele Klein, Alkisti Kitsiou, Isabell Greeve, Anja Gerstner, Leonard Wulff, Wolf-Rüdiger Schäbitz, Lars Timmermann, Andreas Rogalewski
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Neurological Research and Practice, Vol 5, Iss 1, Pp 1-16 (2023)
Druh dokumentu: article
ISSN: 2524-3489
DOI: 10.1186/s42466-023-00291-3
Popis: Abstract Background Evaluation of outcome after stroke is largely based on assessment of gross function 3 months after stroke onset using scales such as mRS. Cognitive or social functions, level of symptom burden or emotional health are not usually assessed, nor are data available on long-term functional outcomes years after stroke. Methods Analysis of 1141 patients with AIS treated with IVT from two major German university hospitals between 2017 and 2020. Patient characteristics and short-term outcome were analysed from patient records. Long-term outcome of 228 patients with prior written informed consent was assessed via telephone survey using mRS and PROMs (EQ-5D-5L, EQ-VAS) 2.5 years after stroke. Results Predictors of excellent to good long-term outcome were younger age, event to door time ≤ 2 h, NIHSS ≤ 6 on admission and NIHSS ≤ 6 after IVT. Stroke recurrence was a negative predictor. Predictors of excellent quality of life at 2.5 years included age
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