Genome-wide association analysis and replication in 810,625 individuals with varicose veins

Autor: Waheed-Ul-Rahman Ahmed, Sam Kleeman, Michael Ng, Wei Wang, Adam Auton, andMe Research Team, Regent Lee, Ashok Handa, Krina T. Zondervan, Akira Wiberg, Dominic Furniss
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-022-30765-y
Popis: Although varicose veins are a common condition, the genetic basis is not well understood. Here, the authors find genetic variants associated with varicose veins and show that a higher polygenic risk score for varicose veins correlates with a greater likelihood of patients undergoing surgical treatment.
Databáze: Directory of Open Access Journals