Plasma Lipid Levels in Relation to Disease Severity in Sickle Cell Anaemia in Abakaliki, Southeast Nigeria

Autor:	Nnachi OC, Edenya OO, Okoye HC, Akpa CO, Nwani FO, Nwani EI
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	cholesterol haemoglobinopathy high-density lipoprotein-cholesterol sickle cell disease total cholesterol Medicine (General) R5-920 Public aspects of medicine RA1-1270
Zdroj:	Annals of Health Research, Vol 9, Iss 3, Pp 247-257 (2023)
Druh dokumentu:	article
ISSN:	2476-8642 2536-6149
DOI:	10.30442/ahr.0903-08-210
Popis:	Background: Dyslipidaemia has been implicated in the pathophysiology of sickle cell disease (SCD) complications; hence its role requires further elucidation. Objectives: To investigate the relationship between disease severity and plasma lipid levels of patients with sickle cell anaemia. Methods: A cross-sectional study design was used for the survey. A total of 50 patients with sickle cell anaemia and 50 controls without SCD were recruited for the study. The clinical data and plasma lipid levels of lipids and haemoglobin parameters were analysed. Results: The majority of the participants were aged 18-25 years. Total plasma cholesterol and HDL-C were significantly lower in individuals with SCA compared with the controls (3.3±1.2 vs 4.2±1.2; p
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/68c316d8e0f74b73ac2c0caaf857d5f1 Zobrazit plný text záznamu View record in DOAJ